Rare case of low-grade mucinous neoplasia of the vermiform appendix

case study

Authors

DOI:

https://doi.org/10.47519/risi.v3i00.16

Keywords:

Pseudomyxoma peritonei, Appendiceal neoplasms, Case report, Surgical treatment

Abstract

Mucinous neoplasms of the vermiform appendix constitute a rare and heterogeneous group of tumors characterized by abnormal mucin production and variable biological behavior. This is a descriptive and retrospective case study reporting a rare case of Low-Grade Mucinous Neoplasm of the Vermiform Appendix, treated at a general surgery referral center. The patient presented with a clinical course compatible with an initially nonspecific acute abdominal condition, which progressed within 24 hours to localized pain in the right iliac fossa, associated with clinical signs suggestive of surgical pathology. Clinical evaluation and physical examination, with a positive Blumberg sign, were decisive for the indication of surgical intervention. The findings reinforce the fundamental role of histopathological analysis for diagnostic confirmation, as well as the relevance of imaging studies in assessing the extent of the disease and in planning surgical treatment. The choice of individualized therapeutic approach proved essential for the patient's favorable clinical evolution, highlighting the need for careful management to prevent complications such as peritoneal dissemination.

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Author Biographies

Eduardo Barbosa Lopes, Alto Vale do Rio do Peixe University

Alto Vale do Rio do Peixe University (UNIARP), Caçador – Santa Catarina (SC) – Brazil. Medical degree from UNIARP; completed his residency in General Surgery at São José Municipal Hospital in Joinville and in Bariatric Surgery at Gastrobese in Passo Fundo. Master’s degree in Society and Development and doctoral candidate at UNIARP. Professor in the medical program at UNIARP, surgeon at Maice Hospital, head of the Bariatric Surgery Department at Maice Hospital, surgeon at the Caçador Municipal Specialty Center, and preceptor for the surgical internship at Maice Hospital. Associate member of the Brazilian Society of Bariatric and Metabolic Surgery.

Cristianne Confessor Castilho Lopes, University of the Joinville Region

University of the Joinville Region (UNIVILLE), Joinville – Santa Catarina (SC) – Brazil. Bachelor’s degree in Physical Therapy from the School of Health Sciences of Joinville. PhD and Master’s degree in Health and Environment from Univille; Specialist in Orthopedic and Traumatology Physical Therapy, Cardiorespiratory Physical Therapy, Functional Dermatological Physical Therapy, Family Health Program, and Higher Education Teaching; COESAS Member of the Brazilian Society of Bariatric and Metabolic Surgery and of the bariatric surgery team in Caçador. Reviewer for the following journals: Taylor and Francis, Wiley Online Library, PubMed, Web of Science (Clarivate), Scielo, Cambridge University Press, BP International; Editorial Advisor for the Journal of Internal Medicine and Emergency Research, Frontiers in Nutrition, Epidemiology International Journal, TRM Non-Drug Therapy, International Journal of Family Medicine and Primary Care, and Journal of Clinical Surgery and Surgical Research.

Fábio Herget Pitanga, Alto Vale do Rio do Peixe University

Alto Vale do Rio do Peixe University (UNIARP), Caçador – Santa Catarina (SC) – Brazil. Medical degree from the Federal University of Paraná (1998), with a residency in Internal Medicine also from UFPR (2001) and a specialization in Endocrinology and Metabolism from the Brazilian Society of Endocrinology and Metabolism (2004 and 2007). Former Full Professor of Endocrinology at the University of Western Santa Catarina (2006–2013). Currently has a private practice specialized in endocrine and metabolic disorders, serving as a leading authority in the midwestern region of Santa Catarina. He also works at the Medical Clinic of Maicé Hospital in the municipality of Caçador (SC). Holds a master's degree and is pursuing a doctorate with a CNPq scholarship in Development and Society at UNIARP; he also serves as a professor for the Problem-Based Learning module in the medical program at the same institution. Full Professor and coordinator of the Endocrinology and Metabolism Clinic (UNIARP). Advisor to the Academic League of Endocrinology at UNIARP, treasurer for the current administration of the Brazilian Society of Endocrinology, Santa Catarina Chapter, and Director of Undergraduate Studies for the Caçador Chapter of the Santa Catarina State Medical Association. Coordinates and organizes the annual Interdisciplinary Congress on Diabetes and Obesity and the Symposium on Endocrinology and Metabolism of the Academic League of Endocrinology and Metabolism.

Lucas Castilho Lopes, Alto Vale do Rio do Peixe University

Alto Vale do Rio do Peixe University (UNIARP), Caçador – Santa Catarina (SC) – Brazil. Medical degree from the Federal University of Santa Catarina, postgraduate degree in Public Health with a focus on the Family Health Program (PSF) from Ibra College, master’s degree and Ph.D. candidate in Development and Society at UNIARP. Professor in the Medical School at UNIARP.

Maria Eduarda Castilho Lopes, Alto Vale do Rio do Peixe University

Universidade Alto Vale do Rio do Peixe (UNIARP), Caçador – Santa Catarina (SC) – Brasil. Graduanda do curso de Medicina da UNIARP.

Larissa Silva Guimarães, Belo Horizonte University Center

Belo Horizonte University Center (UNIBH), Belo Horizonte – Minas Gerais (MG) – Brazil. Currently pursuing a postgraduate degree in Critical Care Medicine at the Brazilian Association of Critical Care Medicine and a postgraduate degree in Emergency Medicine at Terzius College. Currently pursuing an MBA in Health Management from BBI of Chicago. Coordinator of the Study Group on Didactics Applied to Medical Education.

Kaio Rickson Rocha dos Reis da Silva, Amazonas Estácio College

Amazonas Estácio College (ESTÁCIO AMAZONAS), Manaus – Amazonas (AM) – Brazil. Bachelor’s degree in Business Administration from the Federal University of Amazonas and in Nutrition from Estácio University of Amazonas. Master’s degree in Weight Loss and Metabolism from Uniguaçu College. Certified Sports and Nutrition Coach by Link Education.

Vitor Ohana Marques Azzini, State University of Rio de Janeiro

State University of Rio de Janeiro (UERJ), Rio de Janeiro – Rio de Janeiro (RJ) – Brazil. Medical degree from UERJ, with postgraduate degrees in Ophthalmology and Sports Medicine, working in health promotion, prevention, and evidence-based performance optimization.

Tulio Gamio Dias, University of São Paulo

Universidade de São Paulo (USP), São Paulo – São Paulo (SP) – Brasil. Licenciado em Educação Física pela Universidade Federal de Pelotas (1999) e Especialista em Treinamento Desportivo (2001) pela mesma instituição. Mestre em Ciências da Atividade Física pela EACH-USP (2019). Doutorando em Saúde e Meio ambiente pela UNIVILLE.

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Published

2026-03-31

How to Cite

LOPES, Eduardo Barbosa et al. Rare case of low-grade mucinous neoplasia of the vermiform appendix: case study. Ibero-American Journal of Integrative Health, Bauru, São Paulo, Brasil, v. 3, n. 00, p. e026002, 2026. DOI: 10.47519/risi.v3i00.16. Disponível em: https://revistasaude.editoraiberoamericana.com/saude/article/view/16. Acesso em: 11 apr. 2026.

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(2026), v. 3, Publicação Contínua

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